This research presents a virtual reality (VR) for fire evacuation training and a natural user interface via Kinect for imitating users’ movements, e.g. walking, running, step side way, turn and open/close a door, during the training. The incident is set in a realistic environment by imitating one campus building in Bangkok University, where there are robotic, computer, and research laboratories, lecture rooms, and staff offices. The fire starting can be randomly changed to let trainees learn the exit path through the building.